![yuth image](http://lifenity.uk/LIFENITY_UK_DOCS/885_Rheumatoid_Factor.jpg)
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A diverse collection of autoantibodies directed against the antigenic determinants on the Fc-region of IgG molecules is known as rheumatoid factors. They are present in many non-rheumatic disorders as well as other inflammatory rheumatic diseases, and they are crucial in the diagnosis of rheumatoid arthritis.