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A class of hydrolases known as amylases breaks down complex carbs into smaller pieces. To help break down starch, the salivary glands and exocrine pancreas generate amylase. The mucosa of the small intestine, the ovaries, the placenta, the liver, and the fallopian tubes all manufacture it as well. Pancreatic diagnostics heavily relies on α-amylase findings due to the scarcity of some clinical signs associated with pancreatic disorders. They are mostly employed in the identification and observation of acute pancreatitis. H However, macroamylasemia can also occur in cases of renal failure (reduced glomerular filtration), ovaries or lung tumours, pulmonary inflammation, diseases of the salivary gland, diabetic ketoacidosis, cerebral trauma, surgical procedures, and acute pancreatitis or the inflammatory phase of chronic pancreatitis.

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