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Thyrotropin, also known as thyroid stimulating hormone (TSH), is a glycoprotein made up of two subunits and with a molecular weight of about 30,000 daltons. TSH has a diurnal secretion sequence and is produced in particular basophil cells of the anterior pituitary. The primary regulatory mechanism for the biological action of thyroid hormones is the hypophyseal release of thyrotropic hormone (TSH). TSH has a proliferative effect in addition to boosting thyroid hormone production and secretion at all stages. The first test in thyroid diagnostics is the measurement of TSH. The TSH level responds significantly more strongly to even minute variations in the free thyroid hormone concentrations. As a result, TSH is an extremely sensitive and precise metric for evaluating thyroid function. It is especially well-suited for the early identification or rule-out of illnesses affecting the major regulatory circuit that connects the thyroid, pituitary, and brain.

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