Carcino Embryonic Antigen

The foetal gastrointestinal tract and foetal serum are the primary locations of CEA. In addition, healthy adult pancreatic, hepatic, and intestinal tissue have trace amounts of it. After birth, CEA generation is suppressed, and as a result, serum CEA levels are rarely detectable in healthy individuals. In many situations, colorectal adenocarcinomas have high CEA concentrations.3. Twenty to fifty percent of benign disorders affecting the intestines, pancreas, liver, and lungs (such as liver cirrhosis, chronic hepatitis, pancreatitis, ulcerative colitis, Crohn's disease, and emphysema) have mild to moderate CEA increases. Additionally, smokers' CEA values are higher. The primary purpose of CEA determinations is to monitor and manage colorectal cancer therapy. Patients with medullary thyroid carcinoma and tumours of the breast, gastrointestinal system, liver, lung, ovarian, pancreatic, and prostatic organs may have elevated levels. Patients with primary colorectal cancer may also have elevated levels. It is not advised to use CEA results for cancer screening in the general public. Normal range CEA values do not rule out the possibility of a malignant illness.